Seminario DBB: Prof. Stefano Fumagalli

Venerdì 25 Ottobre 2024
Aula Buzzati Traverso, 1 p.m.
Dipartimento di Biologia e Biotecnologie

"Role of the mTOR-downstream effector S6K in Tuberous Sclerosis Complex Neurological Manifestations"

Stefano Fumagalli
Director of Research INSERM,
Institute Necker Enfants Malades (INEM), Paris

Tuberous sclerosis complex (TSC) is a disease caused by constitutive
activation of the mTOR pathway. The presentation will concentrate on
the contribution of the mTOR downstream effector S6 kinase (S6K) in a
mouse model of the disease and on the role played by one of its
substrates, the potassium channel TREK1, in the neurological
manifestation of TSC.