The following opportunity is highlighted:

"I am looking for a motivated person to work in my group on the project “PROtein interactome to sustain seed Storage Protein synthesis in the ER – PROSPER” PRIN-MUR.

The study concerns the molecular mechanisms underlying the synthesis and accumulation of seed storage proteins (SSPs). In particular, we are interested in the network of molecular helpers that take care and assist SSP synthesis, both under physiological and stress conditions, whose activity is closely related to the quality and quantity of protein in the mature seeds.

Folding and assembly of SSPs in the endoplasmic reticulum (ER) is controlled by interactions with ER-resident chaperones and enzymes in a polypeptide-specific manner. Environmental stresses could perturb SSP proteostasis, triggering a transcriptional/translational response called “Unfolded Protein Response – (UPR).

Biochemical, molecular biology and microscopy approaches will be used to identify SSP-specific molecular helpers. The most promising candidates will be functionally characterized using gene editing and/or gene-tagging techniques.

For further information on this research topic see:

• Vitale A. and Pedrazzini E. Front. Plant Sci. 2022 13:869008 https://doi.org/10.3389/fpls.2022.869008
• Brocca et al. Plant Physiology 2021 187:1428–1444 https://doi:10.1093/plphys/kiab367
• Arcalis et al. Int. J. Mol. Sci. 2021, 22, 12671 https://doi.org/10.3390/ijms222312671

The grant will have a duration of 12 months, with a possible extension until the end of the project.

The call will close February, 2nd 2024 (link at https://bandi.urp.cnr.it/doc-assegni/documentazione/15641_DOC_IT.pdf

Master's degree graduated please contact me informally by e-mail.

E-mail emanuela.pedrazzini@ibba.cnr.it

The addition to the admissions ranking for the Master's Degree+ in Advanced Biotechnology, freshmen cohort 2022-23, has been published.

The ranking of admissions to the Master's Degree+ in Advanced Biotechnology, freshmen cohort 2022-23, has been published.